MMI-0100 ameliorates lung inflammation in a mouse model of acute respiratory distress syndrome by reducing endothelial expression of ICAM-1

PURPOSE: ICAM-1 plays a critical role in the development of acute respiratory distress syndrome (ARDS). MK2 regulates the expression of ICAM-1 in human pulmonary microvascular endothelial cells. To explore whether the inhibition of MK2 activation has the same effect in experimental animals, MMI-0100...

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Detalles Bibliográficos
Autores principales: He, Binchan, Geng, Shen, Zhou, Wei, Rui, Yuwen, Mu, Xianmin, Zhang, Chen, You, Qiang, Su, Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Short Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6296205/
https://www.ncbi.nlm.nih.gov/pubmed/30587921
http://dx.doi.org/10.2147/DDDT.S188095

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6296205/
https://www.ncbi.nlm.nih.gov/pubmed/30587921
http://dx.doi.org/10.2147/DDDT.S188095

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