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Gamma linolenic acid regulates PHD2 mediated hypoxia and mitochondrial apoptosis in DEN induced hepatocellular carcinoma

INTRODUCTION: Hepatocellular carcinoma (HCC) is one of the known major health problems across the globe, and is sixth ranked among all cancer, due to its high mortality rate. Polyunsaturated fatty acids (PUFAs) play an important role in the formation of a cell membrane, along with the fluidity of th...

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Detalles Bibliográficos
Autores principales: Cui, Hong, Han, Feng, Zhang, Ling, Wang, Li, Kumar, Mukesh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6296206/
https://www.ncbi.nlm.nih.gov/pubmed/30587920
http://dx.doi.org/10.2147/DDDT.S178519