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Role of Lin28A/let-7a/c-Myc Pathway in Growth and Malignant Behavior of Papillary Thyroid Carcinoma

BACKGROUND: Lin28 is a gene involved in many biological processes, including development, glucose metabolism, and tumorigenesis. Let-7 miRNA is a tumor-suppressor gene that is frequently inactivated in cancer cells. The role of c-Myc (a target gene of let-7) and the Lin28-let-7-c-Myc pathway in the...

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Detalles Bibliográficos
Autores principales: Huang, Jiaqi, Lin, Haishan, Zhong, Muxun, Huang, Jiexiong, Sun, Shuming, Lin, Ling, Chen, Yongsong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6296344/
https://www.ncbi.nlm.nih.gov/pubmed/30531691
http://dx.doi.org/10.12659/MSM.908628