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Role of Lin28A/let-7a/c-Myc Pathway in Growth and Malignant Behavior of Papillary Thyroid Carcinoma
BACKGROUND: Lin28 is a gene involved in many biological processes, including development, glucose metabolism, and tumorigenesis. Let-7 miRNA is a tumor-suppressor gene that is frequently inactivated in cancer cells. The role of c-Myc (a target gene of let-7) and the Lin28-let-7-c-Myc pathway in the...
Autores principales: | Huang, Jiaqi, Lin, Haishan, Zhong, Muxun, Huang, Jiexiong, Sun, Shuming, Lin, Ling, Chen, Yongsong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
International Scientific Literature, Inc.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6296344/ https://www.ncbi.nlm.nih.gov/pubmed/30531691 http://dx.doi.org/10.12659/MSM.908628 |
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