Genome wide association study to identify predictors for severe skin toxicity in colorectal cancer patients treated with cetuximab

EGFR-antibodies are associated with significant skin toxicity, including acneiform rash and folliculitis. It remains impossible to predict the occurrence of severe skin toxicity due to the lack of predictive markers. Here, we present the first genome-wide association study (GWAS) to find single nucl...

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Detalles Bibliográficos
Autores principales: Baas, Jara, Krens, Lisanne, Bohringer, Stefan, Mol, Linda, Punt, Cornelis, Guchelaar, Henk-Jan, Gelderblom, Hans
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6296548/
https://www.ncbi.nlm.nih.gov/pubmed/30557370
http://dx.doi.org/10.1371/journal.pone.0208080

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6296548/
https://www.ncbi.nlm.nih.gov/pubmed/30557370
http://dx.doi.org/10.1371/journal.pone.0208080

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