cPLA(2)α(-/-) sympathetic neurons exhibit increased membrane excitability and loss of N-Type Ca(2+) current inhibition by M(1) muscarinic receptor signaling

Group IVa cytosolic phospholipase A(2) (cPLA(2)α) mediates GPCR-stimulated arachidonic acid (AA) release from phosphatidylinositol 4,5-bisphosphate (PIP(2)) located in plasma membranes. We previously found in superior cervical ganglion (SCG) neurons that PLA(2) activity is required for voltage-indep...

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Detalles Bibliográficos
Autores principales: Liu, Liwang, Bonventre, Joseph V., Rittenhouse, Ann R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6296557/
https://www.ncbi.nlm.nih.gov/pubmed/30557348
http://dx.doi.org/10.1371/journal.pone.0201322

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6296557/
https://www.ncbi.nlm.nih.gov/pubmed/30557348
http://dx.doi.org/10.1371/journal.pone.0201322

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