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Correcting for natural isotope abundance and tracer impurity in MS-, MS/MS- and high-resolution-multiple-tracer-data from stable isotope labeling experiments with IsoCorrectoR

Experiments with stable isotope tracers such as (13)C and (15)N are increasingly used to gain insights into metabolism. However, mass spectrometric measurements of stable isotope labeling experiments should be corrected for the presence of naturally occurring stable isotopes and for impurities of th...

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Detalles Bibliográficos
Autores principales: Heinrich, Paul, Kohler, Christian, Ellmann, Lisa, Kuerner, Paul, Spang, Rainer, Oefner, Peter J., Dettmer, Katja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6297158/
https://www.ncbi.nlm.nih.gov/pubmed/30559398
http://dx.doi.org/10.1038/s41598-018-36293-4