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High MYC Levels Favour Multifocal Carcinogenesis

The term “field cancerisation” describes the formation of tissue sub-areas highly susceptible to multifocal tumourigenesis. In the earlier stages of cancer, cells may indeed display a series of molecular alterations that allow them to proliferate faster, eventually occupying discrete tissue regions...

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Detalles Bibliográficos
Autores principales: Sollazzo, Manuela, Genchi, China, Paglia, Simona, Di Giacomo, Simone, Pession, Annalisa, de Biase, Dario, Grifoni, Daniela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6297171/
https://www.ncbi.nlm.nih.gov/pubmed/30619451
http://dx.doi.org/10.3389/fgene.2018.00612