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Maternal High-Protein and Low-Protein Diets Perturb Hypothalamus and Liver Transcriptome and Metabolic Homeostasis in Adult Mouse Offspring

Early life nutritional imbalances are risk factors for metabolic dysfunctions in adulthood, but the long term effects of perinatal exposure to high versus low protein diets are not completely understood. We exposed C57BL/6J offspring to a high protein/low carbohydrate (HP/LC) or low protein/high car...

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Detalles Bibliográficos
Autores principales: Martin, Lisa J., Meng, Qingying, Blencowe, Montgomery, Lagarrigue, Sandrine, Xiao, Sheila, Pan, Calvin, Wier, Julian, Temple, William C., Devaskar, Sherin U., Lusis, Aldons J., Yang, Xia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6297185/
https://www.ncbi.nlm.nih.gov/pubmed/30619467
http://dx.doi.org/10.3389/fgene.2018.00642