Anti-Invasive and Anti-Proliferative Effects of shRNA-Loaded Poly(Lactide-Co-Glycolide) Nanoparticles Following RAN Silencing in MDA-MB231 Breast Cancer Cells

BACKGROUND: Overexpression of the RAN GTP (RAN) gene has been shown to be linked to metastatic activity of MDA-MB231 human breast cancer cells by increasing Ras/MEK/ERK and PI3K/Akt/mTORC1 signalling. The aim of this study was to investigate the potential of polymeric nanoparticles to deliver two no...

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Detalles Bibliográficos
Autores principales: Sharma, Ankur, McCarron, Paul, Matchett, Kyle, Hawthorne, Susan, El-Tanani, Mohamed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2018
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6297200/
https://www.ncbi.nlm.nih.gov/pubmed/30560466
http://dx.doi.org/10.1007/s11095-018-2555-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6297200/
https://www.ncbi.nlm.nih.gov/pubmed/30560466
http://dx.doi.org/10.1007/s11095-018-2555-6

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