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The Effect of Intrahippocampal Insulin Infusion on Spatial Cognitive Function and Markers of Neuroinflammation in Diet-induced Obesity

Obesity and high fat diet consumption contribute to the development of metabolic disorders, insulin resistance, neuroinflammation, and cognitive impairments. CNS administration of insulin into the brain can attenuate these cognitive impairments. The present study investigated whether hippocampal-dep...

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Detalles Bibliográficos
Autores principales: Gladding, Joanne M., Abbott, Kirsten N., Antoniadis, Christopher P., Stuart, Angela, Begg, Denovan P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6297211/
https://www.ncbi.nlm.nih.gov/pubmed/30619085
http://dx.doi.org/10.3389/fendo.2018.00752