Enhanced astrocyte responses are driven by a genetic risk allele associated with multiple sclerosis

Epigenetic annotation studies of genetic risk variants for multiple sclerosis (MS) implicate dysfunctional lymphocytes in MS susceptibility; however, the role of central nervous system (CNS) cells remains unclear. We investigated the effect of the risk variant, rs7665090(G), located near NFKB1, on a...

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Detalles Bibliográficos
Autores principales: Ponath, Gerald, Lincoln, Matthew R., Levine-Ritterman, Maya, Park, Calvin, Dahlawi, Somiah, Mubarak, Mayyan, Sumida, Tomokazu, Airas, Laura, Zhang, Shun, Isitan, Cigdem, Nguyen, Thanh D., Raine, Cedric S., Hafler, David A., Pitt, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6297228/
https://www.ncbi.nlm.nih.gov/pubmed/30559390
http://dx.doi.org/10.1038/s41467-018-07785-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6297228/
https://www.ncbi.nlm.nih.gov/pubmed/30559390
http://dx.doi.org/10.1038/s41467-018-07785-8

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