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Enhanced astrocyte responses are driven by a genetic risk allele associated with multiple sclerosis
Epigenetic annotation studies of genetic risk variants for multiple sclerosis (MS) implicate dysfunctional lymphocytes in MS susceptibility; however, the role of central nervous system (CNS) cells remains unclear. We investigated the effect of the risk variant, rs7665090(G), located near NFKB1, on a...
Autores principales: | Ponath, Gerald, Lincoln, Matthew R., Levine-Ritterman, Maya, Park, Calvin, Dahlawi, Somiah, Mubarak, Mayyan, Sumida, Tomokazu, Airas, Laura, Zhang, Shun, Isitan, Cigdem, Nguyen, Thanh D., Raine, Cedric S., Hafler, David A., Pitt, David |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6297228/ https://www.ncbi.nlm.nih.gov/pubmed/30559390 http://dx.doi.org/10.1038/s41467-018-07785-8 |
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