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A rapid and robust method for single cell chromatin accessibility profiling

The assay for transposase-accessible chromatin using sequencing (ATAC-seq) is widely used to identify regulatory regions throughout the genome. However, very few studies have been performed at the single cell level (scATAC-seq) due to technical challenges. Here we developed a simple and robust plate...

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Detalles Bibliográficos
Autores principales: Chen, Xi, Miragaia, Ricardo J., Natarajan, Kedar Nath, Teichmann, Sarah A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6297232/
https://www.ncbi.nlm.nih.gov/pubmed/30559361
http://dx.doi.org/10.1038/s41467-018-07771-0