Synthesis and Kinetic evaluation of an azido analogue of methylerythritol phosphate: a Novel Inhibitor of E. coli YgbP/IspD

As multidrug resistant pathogenic microorganisms are a serious health menace, it is crucial to continuously develop novel medicines in order to overcome the emerging resistance. The methylerythritol phosphate pathway (MEP) is an ideal target for antimicrobial development as it is absent in humans bu...

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Detalles Bibliográficos
Autores principales: Baatarkhuu, Zoljargal, Chaignon, Philippe, Borel, Franck, Ferrer, Jean-Luc, Wagner, Alain, Seemann, Myriam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6297244/
https://www.ncbi.nlm.nih.gov/pubmed/30559447
http://dx.doi.org/10.1038/s41598-018-35586-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6297244/
https://www.ncbi.nlm.nih.gov/pubmed/30559447
http://dx.doi.org/10.1038/s41598-018-35586-y

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