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Association of CHFR Promoter Methylation with Treatment Outcomes of Irinotecan-Based Chemotherapy in Metastatic Colorectal Cancer

Aberrant promoter methylation plays a vital role in colorectal carcinogenesis. However, its role in treatment responses is unclear, especially for metastatic disease. Here, we investigated the association between promoter methylation and treatment outcomes of irinotecan-based chemotherapy in 102 pat...

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Detalles Bibliográficos
Autores principales: Cha, Yongjun, Kim, Sun Young, Yeo, Hyun Yang, Baek, Ji Yeon, Choi, Moon Ki, Jung, Kyung Hae, Dong, Seung Myung, Chang, Hee Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6297269/
https://www.ncbi.nlm.nih.gov/pubmed/30562637
http://dx.doi.org/10.1016/j.neo.2018.11.010