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A Meta-Analysis of α-Synuclein Multiplication in Familial Parkinsonism

Chronic alpha-synuclein (SNCA) overexpression is a relatively homogenous and well-defined cause of parkinsonism and dementia. Parkinson's disease (PD), PD with dementia, dementia with Lewy bodies and multiple system atrophy all manifest in SNCA multiplication families. Herein we summarize genea...

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Detalles Bibliográficos
Autores principales: Book, Adam, Guella, Ilaria, Candido, Tara, Brice, Alexis, Hattori, Nobutaka, Jeon, Beomseok, Farrer, Matthew J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6297377/
https://www.ncbi.nlm.nih.gov/pubmed/30619023
http://dx.doi.org/10.3389/fneur.2018.01021