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Esomeprazole Increases Airway Surface Liquid pH in Primary Cystic Fibrosis Epithelial Cells

Respiratory failure, driven by airways mucus obstruction, chronic inflammation and bacterial infections, is the main cause of mortality and morbidity in people with cystic fibrosis (CF) due to defects in the Cl(-) and [Formula: see text] transport activity of the CF Transmembrane conductance Regulat...

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Detalles Bibliográficos
Autores principales: Delpiano, Livia, Thomas, Joseph J., Yates, Annabel R., Rice, Sarah J., Gray, Michael A., Saint-Criq, Vinciane
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6297391/
https://www.ncbi.nlm.nih.gov/pubmed/30618754
http://dx.doi.org/10.3389/fphar.2018.01462