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The Epigenome in Multiple Myeloma: Impact on Tumor Cell Plasticity and Drug Response

Multiple myeloma (MM) is a clonal plasma cell malignancy that develops primarily in the bone marrow (BM), where reciprocal interactions with the BM niche foster MM cell survival, growth, and drug resistance. MM cells furthermore reshape the BM to their own needs by affecting the different BM stromal...

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Detalles Bibliográficos
Autores principales: De Smedt, Eva, Lui, Hui, Maes, Ken, De Veirman, Kim, Menu, Eline, Vanderkerken, Karin, De Bruyne, Elke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6297718/
https://www.ncbi.nlm.nih.gov/pubmed/30619733
http://dx.doi.org/10.3389/fonc.2018.00566