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Perforant Path Fiber Loss Results in Mnemonic Discrimination Task Deficits in Young Rats

The observation that entorhinal input to the hippocampus declines in old age is well established across human studies and in animal models. This loss of perforant path fibers is exaggerated in individuals with episodic memory deficits and Mild Cognitive Impairment, suggesting that perforant path int...

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Detalles Bibliográficos
Autores principales: Burke, Sara N., Turner, Sean M., Desrosiers, Courtney L., Johnson, Sarah A., Maurer, Andrew P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6297719/
https://www.ncbi.nlm.nih.gov/pubmed/30618655
http://dx.doi.org/10.3389/fnsys.2018.00061