Cargando…

The Use of HPV16-E5, EGFR, and pEGFR as Prognostic Biomarkers for Oropharyngeal Cancer Patients

Background: Anti-epidermal-growth-factor-receptor (EGFR) therapies in combination with radiotherapy are being studied on de-escalation clinical trials for HPV-related oropharyngeal cancer (OPC) patients. The HPV16-E5 oncoprotein increases recycling of activated EGFR to the cell surface, enhancing fa...

Descripción completa

Detalles Bibliográficos
Autores principales: Taberna, Miren, Torres, Montserrat, Alejo, María, Mena, Marisa, Tous, Sara, Marquez, Sandra, Pavón, Miquel A., León, Xavier, García, Jacinto, Guix, Marta, Hijano, Rafael, Bonfill, Teresa, Aguilà, Antón, Lozano, Alicia, Mesía, Ricard, Alemany, Laia, Bravo, Ignacio G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6297752/
https://www.ncbi.nlm.nih.gov/pubmed/30619735
http://dx.doi.org/10.3389/fonc.2018.00589