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The Use of HPV16-E5, EGFR, and pEGFR as Prognostic Biomarkers for Oropharyngeal Cancer Patients
Background: Anti-epidermal-growth-factor-receptor (EGFR) therapies in combination with radiotherapy are being studied on de-escalation clinical trials for HPV-related oropharyngeal cancer (OPC) patients. The HPV16-E5 oncoprotein increases recycling of activated EGFR to the cell surface, enhancing fa...
Autores principales: | Taberna, Miren, Torres, Montserrat, Alejo, María, Mena, Marisa, Tous, Sara, Marquez, Sandra, Pavón, Miquel A., León, Xavier, García, Jacinto, Guix, Marta, Hijano, Rafael, Bonfill, Teresa, Aguilà, Antón, Lozano, Alicia, Mesía, Ricard, Alemany, Laia, Bravo, Ignacio G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6297752/ https://www.ncbi.nlm.nih.gov/pubmed/30619735 http://dx.doi.org/10.3389/fonc.2018.00589 |
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