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CagA increases DNA methylation and decreases PTEN expression in human gastric cancer

Gastric cancer is one of the leading causes of cancer-associated mortality worldwide. Cytotoxin-associated gene A (CagA) has been reported to be associated with gastric diseases. Phosphatase and tensin homolog (PTEN) and tet methylcytosine dioxygenase 1 (Tet1) are important tumor-suppressor genes. T...

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Detalles Bibliográficos
Autores principales: Zhang, Baogui, Zhang, Xiaobei, Jin, Meng, Hu, Lei, Zang, Mingde, Qiu, Weilong, Wang, Shouqi, Liu, Bingya, Liu, Shiqi, Guo, Dongli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6297774/
https://www.ncbi.nlm.nih.gov/pubmed/30431097
http://dx.doi.org/10.3892/mmr.2018.9654