Shear stress augments mitochondrial ATP generation that triggers ATP release and Ca(2+) signaling in vascular endothelial cells

Vascular endothelial cells (ECs) sense and transduce hemodynamic shear stress into intracellular biochemical signals, and Ca(2+) signaling plays a critical role in this mechanotransduction, i.e., ECs release ATP in the caveolae in response to shear stress and, in turn, the released ATP activates P2...

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Detalles Bibliográficos
Autores principales: Yamamoto, Kimiko, Imamura, Hiromi, Ando, Joji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Physiological Society 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6297820/
https://www.ncbi.nlm.nih.gov/pubmed/30141983
http://dx.doi.org/10.1152/ajpheart.00204.2018

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6297820/
https://www.ncbi.nlm.nih.gov/pubmed/30141983
http://dx.doi.org/10.1152/ajpheart.00204.2018

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