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MiR-3188 Inhibits Non-small Cell Lung Cancer Cell Proliferation Through FOXO1-Mediated mTOR-p-PI3K/AKT-c-JUN Signaling Pathway

This study investigated the role of miR-3188 on the proliferation of non-small cell lung cancer cells and its relationship to FOXO1-modulated feedback loop. Two non-small cell lung cancer (NSCLC) cell lines A549 and H1299 were used. RNA silencing was achieved by lentiviral transfection. Cell prolife...

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Detalles Bibliográficos
Autores principales: Wang, Chunyan, Liu, Enqi, Li, Wen, Cui, Jue, Li, Tongxiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6297856/
https://www.ncbi.nlm.nih.gov/pubmed/30618730
http://dx.doi.org/10.3389/fphar.2018.01362