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Absence of MHC-II expression by lymph node stromal cells results in autoimmunity

How lymph node stromal cells (LNSCs) shape peripheral T-cell responses remains unclear. We have previously demonstrated that murine LNSCs, lymphatic endothelial cells (LECs), blood endothelial cells (BECs), and fibroblastic reticular cells (FRCs) use the IFN-γ–inducible promoter IV (pIV) of the MHC...

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Detalles Bibliográficos
Autores principales: Dubrot, Juan, Duraes, Fernanda V, Harlé, Guillaume, Schlaeppi, Anjalie, Brighouse, Dale, Madelon, Natacha, Göpfert, Christine, Stokar-Regenscheit, Nadine, Acha-Orbea, Hans, Reith, Walter, Gannagé, Monique, Hugues, Stephanie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6297861/
https://www.ncbi.nlm.nih.gov/pubmed/30584641
http://dx.doi.org/10.26508/lsa.201800164