CRISPR/Cas9 deletions in a conserved exon of Distal-less generates gains and losses in a recently acquired morphological novelty in flies

Distal-less has been repeatedly co-opted for the development of many novel traits. Here, we document its curious role in the development of a novel abdominal appendage (“sternite brushes”) in sepsid flies. CRISPR/Cas9 deletions in the homeodomain result in losses of sternite brushes, demonstrating t...

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Detalles Bibliográficos
Autores principales: Rajaratnam, Gowri, Supeinthiran, Ahiraa, Meier, Rudolf, Su, Kathy F.Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6297884/
https://www.ncbi.nlm.nih.gov/pubmed/30553946
http://dx.doi.org/10.1016/j.isci.2018.11.036

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6297884/
https://www.ncbi.nlm.nih.gov/pubmed/30553946
http://dx.doi.org/10.1016/j.isci.2018.11.036

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