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CRISPR/Cas9 deletions in a conserved exon of Distal-less generates gains and losses in a recently acquired morphological novelty in flies
Distal-less has been repeatedly co-opted for the development of many novel traits. Here, we document its curious role in the development of a novel abdominal appendage (“sternite brushes”) in sepsid flies. CRISPR/Cas9 deletions in the homeodomain result in losses of sternite brushes, demonstrating t...
Autores principales: | Rajaratnam, Gowri, Supeinthiran, Ahiraa, Meier, Rudolf, Su, Kathy F.Y. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6297884/ https://www.ncbi.nlm.nih.gov/pubmed/30553946 http://dx.doi.org/10.1016/j.isci.2018.11.036 |
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