Detection of mutations in SF3B1, EIF1AX and GNAQ in primary orbital melanoma by candidate gene analysis

BACKGROUND: Ocular melanoma is a rare but often deadly malignancy that arises in the uvea (commonest primary site), conjunctiva or the orbit. Primary orbital melanoma (POM) is exceedingly rare, with approximately 60 cases reported to date. Despite recent advances in our understanding of the genetics...

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Detalles Bibliográficos
Autores principales: Rose, Anna M., Luo, Rong, Radia, Utsav K., Kalirai, Helen, Thornton, Sophie, Luthert, Philip J., Jayasena, Channa N., Verity, David H., Coupland, Sarah E., Rose, Geoffrey E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6297940/
https://www.ncbi.nlm.nih.gov/pubmed/30558566
http://dx.doi.org/10.1186/s12885-018-5190-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6297940/
https://www.ncbi.nlm.nih.gov/pubmed/30558566
http://dx.doi.org/10.1186/s12885-018-5190-z

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