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Variation in proviral content among human genomes mediated by LTR recombination
BACKGROUND: Human endogenous retroviruses (HERVs) occupy a substantial fraction of the genome and impact cellular function with both beneficial and deleterious consequences. The vast majority of HERV sequences descend from ancient retroviral families no longer capable of infection or genomic propaga...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6298018/ https://www.ncbi.nlm.nih.gov/pubmed/30568734 http://dx.doi.org/10.1186/s13100-018-0142-3 |