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Variation in proviral content among human genomes mediated by LTR recombination

BACKGROUND: Human endogenous retroviruses (HERVs) occupy a substantial fraction of the genome and impact cellular function with both beneficial and deleterious consequences. The vast majority of HERV sequences descend from ancient retroviral families no longer capable of infection or genomic propaga...

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Detalles Bibliográficos
Autores principales: Thomas, Jainy, Perron, Hervé, Feschotte, Cédric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6298018/
https://www.ncbi.nlm.nih.gov/pubmed/30568734
http://dx.doi.org/10.1186/s13100-018-0142-3