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CD68, CD163, and matrix metalloproteinase 9 (MMP-9) co-localization in breast tumor microenvironment predicts survival differently in ER-positive and -negative cancers

BACKGROUND: The role of tumor-associated macrophages (TAMs) in the cancer immune landscape and their potential as treatment targets or modulators of response to treatment are gaining increasing interest. TAMs display high molecular and functional complexity. Therefore their objective assessment as b...

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Detalles Bibliográficos
Autores principales: Pelekanou, Vasiliki, Villarroel-Espindola, Franz, Schalper, Kurt A., Pusztai, Lajos, Rimm, David L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6298021/
https://www.ncbi.nlm.nih.gov/pubmed/30558648
http://dx.doi.org/10.1186/s13058-018-1076-x