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GrandPrix: scaling up the Bayesian GPLVM for single-cell data
MOTIVATION: The Gaussian Process Latent Variable Model (GPLVM) is a popular approach for dimensionality reduction of single-cell data and has been used for pseudotime estimation with capture time information. However, current implementations are computationally intensive and will not scale up to mod...
Autores principales: | Ahmed, Sumon, Rattray, Magnus, Boukouvalas, Alexis |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6298059/ https://www.ncbi.nlm.nih.gov/pubmed/30561544 http://dx.doi.org/10.1093/bioinformatics/bty533 |
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