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Comparative assessment of different familial aggregation methods in the context of large and unstructured pedigrees

MOTIVATION: Familial aggregation analysis is an important early step for characterizing the genetic determinants of phenotypes in epidemiological studies. To facilitate this analysis, a collection of methods to detect familial aggregation in large pedigrees has been made available recently. However,...

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Detalles Bibliográficos
Autores principales: Weichenberger, Christian X, Rainer, Johannes, Pattaro, Cristian, Pramstaller, Peter P, Domingues, Francisco S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6298062/
https://www.ncbi.nlm.nih.gov/pubmed/30010787
http://dx.doi.org/10.1093/bioinformatics/bty541