A phase I, randomized, open-label, single-dose, 3-period crossover study to evaluate the drug-drug interaction between ZX008 (fenfluramine HCl oral solution) and a regimen of stiripentol, clobazam, and valproate in healthy subjects

Objective: Phase I, open-label, randomized, single-dose, 3-period crossover study assessing pharmacokinetics (PK) and safety of ZX008, a liquid oral formulation of fenfluramine (FFA) under development for adjunctive treatment of Dravet syndrome and Lennox-Gastaut syndrome, administered with and with...

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Detalles Bibliográficos
Autores principales: Boyd, Brooks, Smith, Steven, Gammaitoni, Arnold, Galer, Bradley S., Farfel, Gail M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dustri-Verlag Dr. Karl Feistle 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6298132/
https://www.ncbi.nlm.nih.gov/pubmed/30336805
http://dx.doi.org/10.5414/CP203276

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6298132/
https://www.ncbi.nlm.nih.gov/pubmed/30336805
http://dx.doi.org/10.5414/CP203276

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