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Insulin depot absorption modeling and pharmacokinetic simulation with insulin glargine 300 U/mL

Objective: Mathematical models of insulin absorption have been used to predict plasma insulin concentrations after administration, but few are specifically applicable to insulin glargine, which precipitates subcutaneously after injection. Materials and methods: The formation and redissolution of sub...

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Detalles Bibliográficos
Autores principales: Lindauer, Klaus, Becker, Reinhard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dustri-Verlag Dr. Karl Feistle 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6298133/
https://www.ncbi.nlm.nih.gov/pubmed/30369394
http://dx.doi.org/10.5414/CP203269