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MicroRNA-22 Controls Aberrant Neurogenesis and Changes in Neuronal Morphology After Status Epilepticus

Prolonged seizures (status epilepticus, SE) may drive hippocampal dysfunction and epileptogenesis, at least partly, through an elevation in neurogenesis, dysregulation of migration and aberrant dendritic arborization of newly-formed neurons. MicroRNA-22 was recently found to protect against the deve...

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Detalles Bibliográficos
Autores principales: Beamer, Edward H., Jurado-Arjona, Jeronimo, Jimenez-Mateos, Eva M., Morgan, James, Reschke, Cristina R., Kenny, Aidan, de Leo, Gioacchino, Olivos-Oré, Luis A., Arribas-Blázquez, Marina, Madden, Stephen F., Merchán-Rubira, Jesús, Delanty, Norman, Farrell, Michael A., O’Brien, Donncha F., Avila, Jesus, Diaz-Hernandez, Miguel, Miras-Portugal, M. Teresa, Artalejo, Antonio R., Hernandez, Felix, Henshall, David C., Engel, Tobias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6298134/
https://www.ncbi.nlm.nih.gov/pubmed/30618601
http://dx.doi.org/10.3389/fnmol.2018.00442