Mitochondrial Complex I Activity Is Required for Maximal Autophagy

Cells adapt to nutrient and energy deprivation by inducing autophagy, which is regulated by the mammalian target of rapamycin (mTOR) and AMPactivated protein kinases (AMPKs). We found that cell metabolism significantly influences the ability to induce autophagy, with mitochondrial complex I function...

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Detalles Bibliográficos
Autores principales: Thomas, Hala Elnakat, Zhang, Yu, Stefely, Jonathan A., Veiga, Sonia R., Thomas, George, Kozma, Sara C., Mercer, Carol A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6298213/
https://www.ncbi.nlm.nih.gov/pubmed/30157433
http://dx.doi.org/10.1016/j.celrep.2018.07.101

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6298213/
https://www.ncbi.nlm.nih.gov/pubmed/30157433
http://dx.doi.org/10.1016/j.celrep.2018.07.101

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