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Mitochondrial Complex I Activity Is Required for Maximal Autophagy
Cells adapt to nutrient and energy deprivation by inducing autophagy, which is regulated by the mammalian target of rapamycin (mTOR) and AMPactivated protein kinases (AMPKs). We found that cell metabolism significantly influences the ability to induce autophagy, with mitochondrial complex I function...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6298213/ https://www.ncbi.nlm.nih.gov/pubmed/30157433 http://dx.doi.org/10.1016/j.celrep.2018.07.101 |