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Correlation between measured and calculated free phenytoin serum concentration in neurointensive care patients with hypoalbuminemia

PURPOSE: In critically ill patients, monitoring free phenytoin concentration is a valuable method for phenytoin-dosage adjustment. However, due to technical difficulties and the high cost of these methods, the Sheiner–Tozer equation is routinely used for estimating free phenytoin concentration in cl...

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Detalles Bibliográficos
Autores principales: Javadi, Seyyede-Sareh, Mahjub, Reza, Taher, Abbas, Mohammadi, Younes, Mehrpooya, Maryam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6298392/
https://www.ncbi.nlm.nih.gov/pubmed/30588130
http://dx.doi.org/10.2147/CPAA.S186322