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Correlation between measured and calculated free phenytoin serum concentration in neurointensive care patients with hypoalbuminemia
PURPOSE: In critically ill patients, monitoring free phenytoin concentration is a valuable method for phenytoin-dosage adjustment. However, due to technical difficulties and the high cost of these methods, the Sheiner–Tozer equation is routinely used for estimating free phenytoin concentration in cl...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6298392/ https://www.ncbi.nlm.nih.gov/pubmed/30588130 http://dx.doi.org/10.2147/CPAA.S186322 |