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Targeting the Wnt/β-catenin pathway in human osteosarcoma cells

Aberrant activation of Wnt signaling has been implicated in human osteosarcoma, which may provide a genetic vulnerability that can be targeted in osteosarcoma treatment. To test whether Wnt activation is necessary for osteosarcoma growth, colony formation, invasion, and metastasis, we treated human...

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Detalles Bibliográficos
Autores principales: Fang, Fang, VanCleave, Ashley, Helmuth, Ralph, Torres, Haydee, Rickel, Kirby, Wollenzien, Hannah, Sun, Hongli, Zeng, Erliang, Zhao, Jing, Tao, Jianning
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6298399/
https://www.ncbi.nlm.nih.gov/pubmed/30613366
http://dx.doi.org/10.18632/oncotarget.26377