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Novel Associations between BRCA1 Variants C.181 T>G (Rs28897672) and Ovarian Crisk in Saudi Females

BACKGROUND: Mutations in BRCA1 gene have been implicated in ovarian cancers, and BRCA testing may be conducted in high-risk women. This study was designed to determine the frequency of three single nucleotide polymorphisms (SNPs) variants in BRCA1 gene and BRCA1 expression in Saudi females with ovar...

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Detalles Bibliográficos
Autores principales: Alyahri, Nora, Abdi, Saba, Khan, Wajahatullah, Elrobh, Mohamed, Addar, Mohammed H., Babay, Zeneb A., Alanazi, Mohamed, Aldaihan, Sooad, Shaik, Jilani, Arafah, Maha, Parine, Narasimha Reddy, Warsy, Arjumand
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sciendo 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6298454/
https://www.ncbi.nlm.nih.gov/pubmed/30820179
http://dx.doi.org/10.2478/jomb-2018-0037