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In vivo RNA structural probing of uracil and guanine base-pairing by 1-ethyl-3-(3-dimethylaminopropyl)carbodiimide (EDC)

Many biological functions performed by RNAs arise from their in vivo structures. The structure of the same RNA can differ in vitro and in vivo owing in part to the influence of molecules ranging from protons to secondary metabolites to proteins. Chemical reagents that modify the Watson–Crick (WC) fa...

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Detalles Bibliográficos
Autores principales: Mitchell, David, Renda, Andrew J., Douds, Catherine A., Babitzke, Paul, Assmann, Sarah M., Bevilacqua, Philip C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6298566/
https://www.ncbi.nlm.nih.gov/pubmed/30341176
http://dx.doi.org/10.1261/rna.067868.118