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In vivo RNA structural probing of uracil and guanine base-pairing by 1-ethyl-3-(3-dimethylaminopropyl)carbodiimide (EDC)
Many biological functions performed by RNAs arise from their in vivo structures. The structure of the same RNA can differ in vitro and in vivo owing in part to the influence of molecules ranging from protons to secondary metabolites to proteins. Chemical reagents that modify the Watson–Crick (WC) fa...
Autores principales: | Mitchell, David, Renda, Andrew J., Douds, Catherine A., Babitzke, Paul, Assmann, Sarah M., Bevilacqua, Philip C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6298566/ https://www.ncbi.nlm.nih.gov/pubmed/30341176 http://dx.doi.org/10.1261/rna.067868.118 |
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