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Dual coding potential of a 2′,5′-branched ribonucleotide in DNA
Branchpoints in RNA templates are highly mutagenic, but it is not known yet whether this also applies to branchpoints in DNA templates. Here, we report how nucleic acid polymerases replicate a 2′,5′-branched DNA (bDNA) molecule. We constructed long-chained bDNA templates containing a branch guanosin...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2019
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6298571/ https://www.ncbi.nlm.nih.gov/pubmed/30361268 http://dx.doi.org/10.1261/rna.068486.118 |