Immature CD8 Single-Positive Thymocytes Are a Molecularly Distinct Subpopulation, Selectively Dependent on BRD4 for Their Differentiation

T cell differentiation in the thymus proceeds in an ordered sequence of developmental events characterized by variable expression of CD4 and CD8 coreceptors. Here, we report that immature single-positive (ISP) thymocytes are molecularly distinct from all other T cell populations in the thymus in the...

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Detalles Bibliográficos
Autores principales: Gegonne, Anne, Chen, Qing-Rong, Dey, Anup, Etzensperger, Ruth, Tai, Xuguang, Singer, Alfred, Meerzaman, Daoud, Ozato, Keiko, Singer, Dinah S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6298745/
https://www.ncbi.nlm.nih.gov/pubmed/29972774
http://dx.doi.org/10.1016/j.celrep.2018.06.007

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6298745/
https://www.ncbi.nlm.nih.gov/pubmed/29972774
http://dx.doi.org/10.1016/j.celrep.2018.06.007

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