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The shape of the bacterial ribosome exit tunnel affects cotranslational protein folding
The E. coli ribosome exit tunnel can accommodate small folded proteins, while larger ones fold outside. It remains unclear, however, to what extent the geometry of the tunnel influences protein folding. Here, using E. coli ribosomes with deletions in loops in proteins uL23 and uL24 that protrude int...
Autores principales: | Kudva, Renuka, Tian, Pengfei, Pardo-Avila, Fátima, Carroni, Marta, Best, Robert B, Bernstein, Harris D, von Heijne, Gunnar |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6298777/ https://www.ncbi.nlm.nih.gov/pubmed/30475203 http://dx.doi.org/10.7554/eLife.36326 |
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