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Heterogeneous absorption of antimicrobial peptide LL37 in Escherichia coli cells enhances population survivability

Antimicrobial peptides (AMPs) are broad spectrum antibiotics that selectively target bacteria. Here we investigate the activity of human AMP LL37 against Escherichia coli by integrating quantitative, population and single-cell level experiments with theoretical modeling. We observe an unexpected, ra...

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Detalles Bibliográficos
Autores principales: Snoussi, Mehdi, Talledo, John Paul, Del Rosario, Nathan-Alexander, Mohammadi, Salimeh, Ha, Bae-Yeun, Košmrlj, Andrej, Taheri-Araghi, Sattar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6298785/
https://www.ncbi.nlm.nih.gov/pubmed/30560784
http://dx.doi.org/10.7554/eLife.38174