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Evaluating associations between the benefits and risks of drug therapy in type 2 diabetes: a joint modeling approach

OBJECTIVE: Precision medicine drug therapy seeks to maximize efficacy and minimize harm for individual patients. This will be difficult if drug response and side effects are positively associated, meaning that patients likely to respond best are at increased risk of side effects. We applied joint lo...

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Detalles Bibliográficos
Autores principales: Dennis, John M, Shields, Beverley M, Jones, Angus G, Pearson, Ewan R, Hattersley, Andrew T, Henley, William E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6298877/
https://www.ncbi.nlm.nih.gov/pubmed/30588118
http://dx.doi.org/10.2147/CLEP.S179555