Preclinical evaluation of Amblyomin-X, a Kunitz-type protease inhibitor with antitumor activity

Amblyomin-X, a Kunitz-type protease inhibitor, is a recombinant protein that selectively induces apoptosis in tumor cells and promotes tumor reduction in vivo in melanoma animal models. Furthermore, Amblyomin-X was able to drastically reduce lung metastasis in a mice orthotopic kidney tumor model. D...

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Detalles Bibliográficos
Autores principales: Maria, Durvanei A., Will, Sonia Elisabete A.L., Bosch, Rosemary V., Souza, Jean G., Sciani, Juliana M., Goldfeder, Mauricio B., Rondon, Giuliana G., Chudzinski-Tavassi, Ana M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6298944/
https://www.ncbi.nlm.nih.gov/pubmed/30581760
http://dx.doi.org/10.1016/j.toxrep.2018.11.014

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6298944/
https://www.ncbi.nlm.nih.gov/pubmed/30581760
http://dx.doi.org/10.1016/j.toxrep.2018.11.014

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