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Uncovering secondary metabolite evolution and biosynthesis using gene cluster networks and genetic dereplication

The increased interest in secondary metabolites (SMs) has driven a number of genome sequencing projects to elucidate their biosynthetic pathways. As a result, studies revealed that the number of secondary metabolite gene clusters (SMGCs) greatly outnumbers detected compounds, challenging current met...

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Detalles Bibliográficos
Autores principales: Theobald, Sebastian, Vesth, Tammi C., Rendsvig, Jakob Kræmmer, Nielsen, Kristian Fog, Riley, Robert, de Abreu, Lucas Magalhães, Salamov, Asaf, Frisvad, Jens Christian, Larsen, Thomas Ostenfeld, Andersen, Mikael Rørdam, Hoof, Jakob Blæsbjerg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6298953/
https://www.ncbi.nlm.nih.gov/pubmed/30560908
http://dx.doi.org/10.1038/s41598-018-36561-3